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Preclinical: Laboratory & animal models Goal: Explore if & how new treatment may work Phase I: Small number (eg, 20-100) of healthy subjects Goal: Evaluate toxicity, maximum tolerated dose, adverse effects, pharmacokinetics & pharmacodynamics of new treatment (safety) Phase II: Small number (eg, up to a few hundred) of affected subjects Goal ...
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Clinical trials are research studies that involve people. Through clinical trials, doctors find new ways to improve treatments and the quality of life for people with disease. In this short clip, Dr. Brigitte Widemann of NCI’s Pediatric Oncology Branch discusses cancer clinical trials and resources for families. https://www.cancer.gov/about-cancer/treatment/clinical-trials/what-are-trials | National Cancer Institute
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